Phytochemical profiling of the bioactive principles of Alysicarpus glumaceus (Vahl) DC. aerial parts

Background and Aims: Alysicarpus glumaceus is a plant used in Africa, Asia some parts of the Arabian Peninsula with folkloric claims having anti-tussive, anti-asthmatic, anti-diarrheal, abortifacient, anti-psychotic, anti-inflammatory, diuretic stimulatory activities. The aim this study was to determine phytoconstituents present methanol extract (ME) its fractions. Methods: Standard qualitative phytochemical screening methods such as thin layer chromatography (TLC), gas mass spectrometry (GC-MS) fourier-transform infrared (FT-IR) spectroscopy were employed for profiling identification phytoconstituents. Results: revealed presence alkaloids, cardiac glycosides, flavonoids, saponins, steroids, tannins terpenes. GC-MS chromatogram showed total 57 peaks 38 different compounds identified, out which 15 fatty acids mainly 3-Quinolinecarboxylic acid, 6,8-difluoro-4-hydroxy-, ethyl ester; cis-Vaccenic acid; 9,12,15-Octadecatrienoic methyl ester, (Z,Z,Z)- Octasiloxane, 1,1,3,3,5,5,7,7,9,9,11,11,13,13,15,15- hexadecamethyl-;1-methyl-4-phenyl-5-thioxo-1,2,4-triazolidin-3-one; 2-Pentanone, 4-hydroxy-4-methyl-; Hexadecanoic Palmitoleic 9,12-Octadecadienoic acid 9,17-Octadecadienal. While FT-IR spectras indicated carbonyl, alcohol, carboxylic aliphatic functional groups. Additionally, acetate fraction peak characteristics aromatic (=C-H)/olefinic (=C-H) group. Conclusion: that major constituents glumaceus.